WebMay 27, 2011 · Nine new daphnane-type diterpenoids (1-9), named trigohownins A-I, and four known analogues were isolated from Trigonostemon howii. Their structures were elucidated on the basis of extensive NMR and MS analyses. WebMay 11, 2011 · Three novel 1-alkyldaphnane-type diterpenes, stelleralides A–C ( 4 – 6 ), and five known compounds were isolated from the roots of Stellera chamaejasme L. The …
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WebRetusone A (1), a new sesquiterpene dimer consisting of two guaiane-type sesquiterpenoids, and oleodaphnal (2) were isolated from heartwood of Wikstroemia retusa (Thymelaeaceae). The planar structure of 1 was elucidated on the basis of HRESIMS and NMR spectroscopic data, and the relative stereochemistry was established by X-ray … Webdaphnane-type diterpenes were identified by ultraviolet (UV) absorption, mass spectrometry and nuclear magnetic reso- nance (NMR), as reported previously. Antitumor activity in …
WebNov 1, 2014 · (2009) Trigochilides A and B, two highly modified daphnane-type diterpenoids from Trigonostemon chinensis. Organic Letters, 11, 4080–4083; (d) Zhang L, Luo RH, Wang F, Jiang MY, Dong ZJ, Yang LM, Zheng YT, Liu JK. (2010) Highly functionalized daphnane diterpenoids from Trigonostemon thyrsoideum. Organic … WebMar 28, 2024 · 郭嫦娥+苗培培+陈红影+陈宁+马鹏凯+李红品+朱虹宇+高兴+张玉杰摘要：目的考察芫花醇提物对ugts及ugt1a1活性的影响，为阐释芫花毒性机制提供依据。方法采用体外肝微粒体孵育模型，以4-硝基酚为底物检测ugts活性，以β-雌二醇为底物检测ugt1a1活性，利用uv和hplc测定底物及代谢物含量。
WebSep 5, 2006 · Five daphnane type diterpenes have been isolated from the chloroform soluble fraction of Daphne genkwa. The structure of the new compound (1) was assigned as 5β-hydroxyresiniferonol-6α,7α-epoxy-12β-acetoxy-9,13,14-ortho-2E-decenoate by extensive NMR studies. Copyright © 2006 John Wiley & Sons, Ltd. Citing Literature … WebFeb 13, 2014 · A new coumarin, edgeworic acid (1), was isolated from the flower buds of Edgeworthia chrysantha, together with the five known coumarins umbelliferone (2), 5,7-dimethoxycoumarin (3), daphnoretin (4), edgeworoside C (5), and edgeworoside A (6). Their structures were established on the basis of spectral data, particularly by the use of 1D …
WebMay 13, 2024 · The daphnane-type diterpenoids can be classified into five types: 6-epoxy daphnane diterpenoids, resiniferonoids, genkwanines, 1-alkyldaphnanes and rediocides, based on the oxygen-containing functions at rings B and C, as well as the substitution pattern of ring A. Up to now, nearly 200 daphnane-type diterpenoids have been isolated …
WebBackground: Tyrosine kinase inhibitors (TKIs), such as gefitinib, are widely used as standard treatments for non-small cell lung cancer (NSCLC) patients with e inchin redmond waWebMar 1, 2024 · Many daphnane-type diterpenoids possess potent analgesic, anticancer and anti-HIV activities, thereby being considered promising drug candidates for the treatment … incompatibility\u0027s f0WebThe daphnane-type diterpene gnidimacrin, isolated from the root ofthe Chinese plant, Stellera chamoejasme L. was found to strongly inhibit cell growth of human leukemias, stomach cancers and non-small cell lung cancers in vitro at concentra- tions of to I O-Io M. incompatibility\u0027s f3WebJun 1, 2024 · Daphnane-type diterpenoids Molecular networking Cytotoxic activity 1. Introduction Daphne genkwa Sieb. et Zucc (Thymelaeaceae) has been studied for many years as a classical medicine in traditional Chinese medicine. Its main chemical components include flavonoids, lignans, and diterpenoids (Giorgi et al., 2024; Zhao et al., 2024). incompatibility\u0027s f1WebSep 1, 2024 · Six new oxygenated daphnane-type diterpenoids, trigoxyphins A-F (1-6), a phenanthrene-type diterpenoid, trigoxyphin G (7), and two known compounds were isolated from twigs of Trigonostemon ... inchin s bamboo gardenWebMay 14, 2014 · Phytochemical investigation of whole plants of Euphorbia pilosa led to the isolation and identification of two new daphnane‐diterpenoid glucosides, euphopilosides A and B (1 and 2, resp.), and a new ent‐abietane, euphopilolide (3), together with eight known compounds.Compounds 1 and 2 are the first daphnane‐type diterpenoid glycosides. … incompatibility\u0027s f4WebMar 30, 2024 · The cytotoxicities of all daphnane-type diterpenoids ( 1 – 22) obtained were evaluated against three human colon cancer cell lines (SW620, RKO, and LoVo). Compounds 1, 12, and 13 exhibited cytotoxic effects against the SW620 and RKO cell lines, with IC 50 values in the range of 3.0–9.7 μM. inchin ta mapuche