Hif1an

WebHIF1AN Antibody (MA5-35391) in WB. Western Blot analysis of HIF1AN performed on normal (control) and HIF1AN knockout (KO) 293T cells using a HIF1AN monoclonal antibody ( Product # MA5-35391) at a dilution of 1:1,000. An HRP Goat Anti-Rabbit IgG (H+L) secondary antibody was applied at a dilution of 1:10,000. WebExpression of HIF1AN (DKFZp762F1811, FIH1, FLJ20615, FLJ22027) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information.

Cancers Free Full-Text Hypoxia-Induced Centrosome ... - MDPI

WebSymbol: Hif1an: Name: hypoxia inducible factor 1 subunit alpha inhibitor: RGD ID: 1308281: Description: Predicted to enable several functions, including 2-oxoglutarate-dependent … Web24 de fev. de 2024 · Human papillomavirus-negative (HPV-neg) oropharyngeal squamous cell carcinomas (OPSCCs) are associated with poorer overall survival (OS) compared with HPV-positive (HPV-pos) OPSCCs. The major obstacle in improving outcomes of HPV-neg patients is the lack of robust biomarkers and therapeutic targets. Herein, we investigated … inclusion\\u0027s 8k https://illuminateyourlife.org

(PDF) Low expression of HIF1AN accompanied by less

Web1 de jul. de 2006 · HIF1AN expression inversely correlates with that of TGFB3, suggesting that HIF1AN may also play a role in modulating the HIF1A transcriptional properties, in particular, the expression of TGFB3. However, our placental explant studies indicate that HIF1AN mRNA expression is not affected by changes in oxygen tension. Web1 de fev. de 2003 · Pubmed ID Year Title Citations; 12080085: 2002: FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. WebHIF1AN Protein Overview. Hypoxia-inducible factor-1 activates transcription of genes whose protein products either increase oxygen availability by promoting erythropoiesis (see EPO; 133170) and angiogenesis (see VEGF; 192240) or mediate adaptive responses to oxygen deprivation, such as increased glycolytic metabolism. inclusion\\u0027s 96

Hif1an MGI Mouse Gene Detail - MGI:2442345 - hypoxia …

Category:Anti-HIF1AN Rabbit Polyclonal Antibody (Alexa Fluor® 647)

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Hif1an

HIF1A - HIF1AN Interaction Summary BioGRID

WebSymbol: HIF1AN: Name: hypoxia inducible factor 1 subunit alpha inhibitor: RGD ID: 1317966: HGNC Page: HGNC:17113: Description: Enables several functions, including 2-oxoglutarate-dependent dioxygenase activity; NF-kappaB binding activity; and transition metal ion binding activity. WebView mouse Hif1an Chr19:44551293-44564713 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression

Hif1an

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WebHIF1A HIF1AN: Affinity Capture-MS. Affinity Capture-MS. An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. Luo W (2010) High-BioGRID- WebHIF1AN (Hypoxia inducible factor 1 alpha inhibitor) is a corepressor that interacts with hypoxia inducible factor 1 (HIF1) alpha and the von Hippel Lindau tumor suppressor …

WebHIF1AN is an asparaginyl hydroxylase enzyme that controls the transcriptional activity of hypoxia-inducible factor. FIH1 is a part of the Fe2+ and 2-oxoglutarate-dependent dioxygenase superfamily, FIH1 is protein that hydoxylates a specific asparagine residue (Asn-803) within the HIF1A C-terminal transactivation domain. WebFlow Cytometry analysis of HeLa (Human cervix adenocarcinoma epithelial cell) cells labeling HIF1AN/FIH-1 with purified ab92498 at 1/1000 dilution (1 µg/mL) (Red). Cells were fixed with 4% Paraformaldehyde and permeabilised with 90% Methanol. A Goat anti rabbit IgG (Alexa Fluor ® 488, ab150077) secondary antibody was used at 1/2000.

WebBiological context of HIF1AN. This hydroxylation is performed by the novel asparaginyl hydroxylase, factor-inhibiting HIF-1 ' ( FIH-1 ), of which HIF-1alpha and HIF-2alpha are the only reported substrates [1]. FH and FIH-1 mutation analysis were performed by single stranded conformational polymorphism and direct sequencing of PCR products [2]. WebView mouse Hif1an Chr19:44551293-44564713 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression

Web1 de mai. de 2024 · Specifically, we mimicked hypoxia pre-conditioning of MSCs via targeted editing of HIF1AN which showed improved therapeutic potential of MSCs. Therefore, targeted gene editing of HIF1AN of MSCs prior to transplantation may hold promise to enhance the therapeutic potential of MSC-based therapy.

Web21 de mar. de 2024 · Authors identified KANK3 as a new substrate for the oxygen sensor hypoxia-inducible factor 1-alpha inhibitor (HIF1AN), which hydroxylates HIF-1/2alpha … inclusion\\u0027s 8oWebPredicted to localize to nucleus and perinuclear region of cytoplasm. Is expressed in several structures, including alar plate midbrain region; central nervous system; immature eye; … inclusion\\u0027s 91Web30 de set. de 2024 · Fig. S3 Dot plot of CpG methylation in HIF1AN in the three study groups, i.e., HAPE-f, HAPE-p and HLs. It revealed 46 CpG sites in HIF1AN CpG island 47. Table S1 Methylation distribution of CpG sites of EGLN1 and HIF1AN in each subject of the three study groups i.e., HAPE-f, HAPE-p and HLs. Table S2 Real-time PCR conditions … inclusion\\u0027s 92Web2 de fev. de 2024 · BackgroundHypoxia-inducible factor 1-alpha (HIF-1α) stability and transcriptional action are reduced by the hypoxia-inducible factor 1-alpha subunit … inclusion\\u0027s 93WebHypoxia-inducible factor 1-alpha inhibitor is a protein that in humans is encoded by the HIF1AN gene. Interactions. HIF1AN has been shown to interact with HIF1A and Von Hippel-Lindau tumor suppressor. … inclusion\\u0027s 9ahttp://www.informatics.jax.org/marker/MGI:2442345 inclusion\\u0027s 8rWebShowing subcellular location of HIF1AN (DKFZp762F1811, FIH1, FLJ20615, FLJ22027). We use cookies to enhance the usability of our website. If you continue, we'll assume … inclusion\\u0027s 8w